Treatment of anticonvulsant osteomalacia with 1 alpha hydroxycholecalciferol.
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چکیده
منابع مشابه
Treatment of osteomalacia associated with primary biliary cirrhosis with oral 1-alpha-hydroxy vitamin D3.
309 Treatment of osteomalacia associated with primary biliary cirrhosis with oral I-alpha-hydroxy vitamin D3 Osteomalacia sometimes occurs in chronic cholestatic liver disease and is usually treated with large doses of parenteral vitamin D, although oral treatment is also effective.' Treatment with oral lcx-hydroxy vitamin D3 (1ox-OHD,), a synthetic analogue of 1,25-dihydroxy vitamin D3, is of ...
متن کاملTreatment of osteomalacia with oral 1-alpha-hydroxyvitamin D3 in a patient with malabsorption.
Vitamin D is now known to undergo 25-hydroxylation in the liver and subsequently 1 a-hydroxylation in the kidney to form 1,25dihydroxyvitamin D, (1,25(OH)2D), before exerting its biological effects.' This knowledge has stimulated investigation into possible therapeutic applications of vitamin D metabolites and their synthetic analogues in metabolic bone disease. 1 a-hydroxyvitamin D3 (1 ocOHD3)...
متن کامل25-Hydroxycholecalciferol absorption in steatorrhoea and postgastrectomy osteomalacia.
Post-absorption levels of 25-hydroxy vitamin D (25-OHD) after oral administration of 25-hydroxycholecalciferol (25-OHD3) were measured in 11 subjects. Five had presented with steatorrhoea of various causes while six had post-gastrectomy osteomalacia. Post-absorption levels of 25-OHD were low in four of the patients with steatorrhoea but normal in five of those with post-gastrectomy osteomalacia...
متن کاملBarbiturate and anticonvulsant treatment in relation to osteomalacia with haemodialysis and renal transplantation.
Among 39 patients treated by regular haemodialysis for four years or more pathological fractures and histological evidence of osteomalacia were significantly more common in those taking barbiturates. Out of 58 transplant recipients surveyed after one year, seven had osteomalacia; four of these had been taking phenobarbitone and phenytoin and one had taken barbiturates alone. Sedatives and other...
متن کاملWhole-body in-vivo neutron activation analysis in assessing treatment of renal osteodystrophy with 1-alpha-hydroxycholecalciferol.
Four selected adults with different patterns of osteodystrophy receiving regular dialysis were treated with 1-alpha-hydroxycholecalciferol (1-alpha-OHD3) 0-5-2 mug/day for 10 to 12 months. In two patients, one with osteitis fibrosa and the other with osteomalacia, significant biochemical, radiological, and histological improvements occurred, and total body calcium measured by in-vivo neutron ac...
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ژورنال
عنوان ژورنال: BMJ
سال: 1977
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.6060.551